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Loan Agreement With SVB [Member] Loan Agreement with SAB Commercial milestone payments. 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Segment Reporting [Abstract] Business Combination, Recognized Asset Acquired, Asset Total identifiable assets acquired Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block] Summary of Financial Instruments Carried at Fair Value on Recurring Basis Business Combinations Business Combination [Policy Text Block] Unrealized losses (gains) on short-term investments Unrealized Gain (Loss) on Investments Liabilities, Current [Abstract] Current liabilities: Related Party Transactions [Abstract] Shares, Outstanding Beginning balance, shares Ending balance, shares Commitments and Contingencies Commitments and contingencies Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value Weighted Average Grant Date Fair Value, Nonvested, Ending Balance Weighted Average Grant Date Fair Value, Nonvested, Beginning Balance General and Administrative Expense [Member] General and Administrative Share Based Compensation Arrangement by Share Based Payment Award, Equity Instruments Other than Options, Expected to Vest, Weighted Average Grant Date Fair Value Share-based compensation arrangement by share-based payment award, equity instruments other than options, expected to vest, weighted average grant date fair value. 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Development income Accrued Liabilities [Member] Accrued Expenses Antidilutive Securities, Name [Domain] Inventory, Net Inventory, Net, Total Inventory Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Total Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation Cash and cash equivalents at beginning of period Cash and cash equivalents at end of period Interest Paid, Excluding Capitalized Interest, Operating Activity Cash paid for interest Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table] Statistical Measurement [Domain] Assets, Current Total current assets Share-Based Payment Arrangement, Expense Total stock-based compensation expense Stock-based compensation expense Document Period End Date Fair Value Hierarchy and NAV [Domain] Identifiable intangible assets, amortization period Acquired Finite-Lived Intangible Assets, Weighted Average Useful Life Statement of Financial Position [Abstract] Business Combination, Recognized Asset Acquired, Asset [Abstract] Identifiable assets acquired Business Combination Recognized Asset Acquired Operating Lease Right-of-use Assets Business combination recognized asset acquired operating lease right-of-use assets. Operating lease right-of-use assets Shelf Registration [Member] Shelf registration member. Shelf Registration [Member] Antidilutive Security, Excluded EPS Calculation [Table] Class of Stock [Axis] Royalty Net Sales Percentage Royalty net sales percentage. Royalty net sales percentage Number of operating leases. Number of operating leases Public Offering [Member] Public Offering. Public Offering Liabilities Total liabilities Operating Costs and Expenses [Abstract] Operating costs and expenses Less: Financial Instruments [Domain] Number of claims outstanding. Number of Claims Outstanding Number of claims outstanding Jefferies LLC [Member] Jefferies LLC. Share-Based Compensation Arrangement by Share-Based Payment Award, Description Performance stock unit, description Lessee, Operating Lease, Liability, to be Paid, Year Two 2028 Charming Jade Limited [Member] Charming Jade Limited. Charming Jade Limited Variable Rate [Axis] Finite-Lived Intangible Assets, Gross Gross Carrying Amount Gross Carrying Amount Weighted Average Number of Shares Outstanding, Diluted, Total Weighted Average Number of Shares Outstanding, Diluted Weighted average shares of common stock outstanding, diluted Weighted-average common stock outstanding, diluted Lessee Operating Lease Liability Payments Due After Year Four Lessee operating lease liability payments due after year four. Thereafter Entity File Number Cover [Abstract] Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Minimum Expected volatility, Minimum Accrued expenses and other current liabilities. Accrued Expenses and Other Current Liabilities [Table] Prepaid Expense and Other Assets, Current Prepaid expenses and other current assets Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period Number of shares, Forfeited Number of shares, Forfeited Additional Term Loan With SVB [Member] Additional Term Loan With SVB [Member] Additional term loan with SVB Number of Operating Segments Number of operating segments Sale of Stock [Domain] Development and regulatory milestone payments. Development and regulatory milestone payments Development and regulatory milestone payments Segment Reporting Disclosure [Text Block] Segment Disclosures General and Administrative Expense, Total General and Administrative Expense General and administrative Revenue from Contract with Customer, Including Assessed Tax Revenue License and collaboration revenue Total revenues Temporary Equity, Liquidation Preference Redeemable convertible preferred stock, liquidation value Number of Outstanding Options, Forfeited/Expired Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures and Expirations in Period, Total Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures and Expirations in Period Number of Outstanding Options, Forfeited/Expired Subsequent Event [Table] Share-Based Compensation Arrangement by Share-Based Payment Award, Shares Issued in Period ESPP shares purchased during period (in shares) Transfers between Level 1 and Level 2 of fair value hierarchy Transfer Between Level One and Level Two of Fair Value Hierarchy Transfer between level one and level two of fair value hierarchy. Finite-Lived Intangible Assets, Net Finite-Lived Intangible Assets, Net, Ending Balance Finite-Lived Intangible Assets, Net, Beginning Balance Net Carrying Amount Intangible assets, net Net Carrying Amount Stock Issuance Costs Accrued But Not Yet Paid Stock issuance costs accrued but not yet paid. Stock issuance costs, unpaid and accrued Significant Accounting Policy. Significant Accounting Policy [Table] Property, Plant and Equipment, Useful Life Property and equipment, weighted average period New Accounting Pronouncements, Policy [Policy Text Block] Recently Issued Accounting Standards Lessee, Operating Lease, Liability, to be Paid, Maturity [Table Text Block] Schedule of Maturities of Lease Liabilities Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Stock Issued During Period, Shares, Conversion of Convertible Securities Conversion of redeemable convertible preferred stock, shares Reclassification of common stock Ownership [Axis] Business Combination, Recognized Liability Assumed, Liability Total liabilities assumed Tranche A and Tranche B Funds [Member] Tranche A and Tranche B funds. Tranche A and Tranche B Funds Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Minimum Risk-free interest rate, Minimum Depreciation expense Depreciation Depreciation, Total Gross unrecognized stock-based compensation expense Share-Based Payment Arrangement, Nonvested Award, Excluding Option, Cost Not yet Recognized, Amount Common Stock, Shares, Outstanding, Beginning Balance Common Stock, Shares, Outstanding, Ending Balance Common Stock, Shares, Outstanding Common Stock, shares outstanding Operating Lease, Liability, Current Operating lease liabilities, current portion Depreciation, Depletion and Amortization, Total Depreciation, Depletion and Amortization Depreciation and amortization Document Transition Report Research and Development Expense Research and development Total research and development Statement of Cash Flows [Abstract] Stock Issued During Period, Value, New Issues Issuance of common stock, net of issuance costs Share-Based Payment Arrangement, Option, Activity [Table Text Block] Summary of Stock Option Activity Equity [Text Block] Common Stock Accounts and Financing Receivables [Table] Finite-Lived Intangible Assets [Line Items] Earnings Per Share [Text Block] Net Loss Per Share Attributable to Common Stockholders Accrued expenses and other current liabilities. Accrued Expenses and Other Current Liabilities [Line Items] Net loss and comprehensive loss Net loss Net loss Weighted average period of unrecognized compensation expense remained to be amortized. Weighted Average Period of Unrecognized Compensation Expense Remained to be Amortized Weighted average period of unrecognized compensation expense remained to be amortized Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value Aggregate Intrinsic Value, Beginning Balance Aggregate Intrinsic Value, Ending Balance Increase (Decrease) in Inventories Increase (Decrease) in Inventories, Total Inventory Operating Lease, Cost Operating lease cost Preferred Stock, Convertible, Shares Issuable Common Stock Issuable Upon Conversion Membership Interest Percentage Membership interest percentage. Membership interest percentage Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate Expected dividend yield License And Collaboration Revenue [Member] License and collaboration revenue. License and Collaboration Revenue Cash paid for amounts included in the measurement of lease liabilities, included in operating cash flows Operating Lease, Payments Assets Assets [Abstract] Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate Risk-free interest rate Construction in Progress [Member] Construction in Progress Prepaid expenses and other current assets Increase (Decrease) in Prepaid Expense and Other Assets Prepaid and current assets Document Fiscal Year Focus Issuance of redeemable convertible preferred stock, shares Issuance Of Redeemable Convertible Preferred Stock Shares Issuance of Series F redeemable convertible preferred stock (inclusive of deemed dividend of $410 to accrete to redemption value), shares Cash Provided by (Used in) Investing Activity, Including Discontinued Operation [Abstract] Investing Activities Accounts Payable, Current, Total Accounts Payable, Current Accounts payable Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested in Period, Fair Value Aggregate grant-date fair value of options vested Research and Development Expense [Member] Research and Development 2026 Finite-Lived Intangible Asset, Expected Amortization, Year One Proceeds from Stock Options Exercised Proceeds from exercise of common stock options Fair Value Disclosures [Abstract] Commitments and Contingencies Disclosure [Abstract] Lessee, Operating Lease, Liability, to be Paid, Year One 2027 Net Income (Loss) Available to Common Stockholders, Basic Net loss attributable to common stockholders Business Combination, Recognized Asset Acquired to Liability Assumed, Excess (Less) Net identifiable assets acquired Working Capital Working capital Working capital. Debt Instrument [Axis] Share-Based Payment Arrangement [Abstract] Gross unrecognized stock-based compensation cost Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount, Total Reserved for Future ESPP Issuances Reserved For Future ESPP Issuances [Member] Reserved for future ESPP issuances. Assets, Fair Value Disclosure, Total Assets, Fair Value Disclosure Assets Sale of Stock [Axis] Business Combination, Recognized Liability Assumed, Deferred Tax Liability Deferred tax liability Cash Provided by (Used in) Investing Activity, Including Discontinued Operation Net cash used in investing activities Title of 12(b) Security Schedule of Segment Reporting Information, by Segment [Table] Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value Weighted Average Grant Date Fair Value, Forfeited Related and Nonrelated Parties [Domain] Temporary Equity, Shares Issued Redeemable convertible preferred stock, shares issued Shares Issued Accounts Payable [Member] Accounts Payable Lessee, Operating Lease, Liability, to be Paid, Remainder of Fiscal Year 2026 Other Liabilities, Noncurrent Other liabilities Employee stock purchase plan. Employee Stock Purchase Plan [Text Block] Employee Stock Purchase Plan Consolidated Entities [Axis] Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Increase (Decrease) in Operating Capital [Abstract] Changes in operating assets and liabilities: Summary of Components of Property and Equipment, Net Property, Plant and Equipment [Table Text Block] Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price Weighted Average Exercise Price, Beginning Balance Weighted Average Exercise Price, Ending Balance Preferred Stock [Text Block] Redeemable Convertible Preferred Stock Cash, cash equivalents and marketable securities. Cash, cash equivalents and marketable securities Cash, cash equivalents and marketable securities Acquisition of Biovire Business Combination [Text Block] Additional Paid-in Capital [Member] Additional Paid-in Capital Note receivable, net Financing Receivable, after Allowance for Credit Loss, Noncurrent Financing Receivable, after Allowance for Credit Loss, Noncurrent, Total Outstanding note receivable Accrued expenses and other current liabilities Increase (Decrease) in Accrued Liabilities and Other Operating Liabilities Measurement Frequency [Domain] Statement of Income Location, Balance [Axis] Trading Symbol Intangible Asset, Finite-Lived [Table] Property and Equipment, Net Property, Plant and Equipment Disclosure [Text Block] Related Party Transaction [Table] Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Maximum Risk-free interest rate, Maximum Extinguishment of Debt [Axis] Subsequent Event Type [Axis] Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract] Financing Activities Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term Expected term (in years) Fair Value, Recurring [Member] Fair Value, Recurring Entity Ex Transition Period Employee stock purchase plan. Employee Stock Purchase Plan [Abstract] Value of Common Stock Issuable Value of common stock issuable. Value of common stock issuable Finite-Lived Intangible Assets, Amortization Expense, Maturity Schedule [Abstract] Lessee, Operating Lease, Liability, to be Paid Total lease payment Lessee, Operating Lease, Liability, Undiscounted Excess Amount Less: amount representing imputed interest Success fee agreement with SVB. Success Fee Agreement With SVB [Member] Success Fee Agreement with SVB Share-Based Compensation Arrangement by Share-Based Payment Award, Maximum Employee Subscription Rate Percentage of earnings applied to purchase of stock under ESPP Equity Components [Axis] Nonoperating Income (Expense) Total other income, net Other income, net Equity Component [Domain] Asset Class [Axis] Goodwill and Intangible Assets Disclosure [Abstract] Summary of Preliminary Purchase Price Allocation Business Combination, Recognized Asset Acquired and Liability Assumed [Table Text Block] 2022 Plan Two thousand twenty two plan. Two Thousand Twenty Two Plan [Member] Business Combination [Axis] IPO [Member] Initial Public Offering Machinery and Equipment [Member] Machinery and Equipment Subsidiaries [Member] SafeGuard Healthcare, LLC [Member] Maximum [Member] Maximum Liabilities, Fair Value Disclosure, Total Liabilities, Fair Value Disclosure Liabilities Statistical Measurement [Axis] Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price Weighted Average Exercise Price, Exercised Finite-Lived Intangible Assets, Accumulated Amortization Accumulated Amortization Receivables, Net, Current Receivables, Net, Current, Total Accounts receivable, net Common Stock, Value, Issued Common stock, $0.0001 par value per share; 700,000,000 and 700,000,000 share authorized as of March 31, 2026 and December 31, 2025, respectively; 88,007,761 and 80,689,128 shares issued and outstanding as of March 31, 2026 and December 31, 2025, respectively Secured Overnight Financing Rate (SOFR) Secured Overnight Financing Rate (SOFR) [Member] Related Party Transaction, Amounts of Transaction Amount paid to related party Preferred Stock Dividends, Income Statement Impact Deemed dividend on redeemable convertible preferred stock issuances Schedule of Finite-Lived Intangible Assets, Future Amortization Expense [Table Text Block] Summary of Estimated Future Amortization Expense Proceeds from Sale of Notes Receivable Payments from note receivable Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate Expected volatility Finite-Lived Intangible Assets by Major Class [Axis] Payment, Tax Withholding, Share-Based Payment Arrangement Withholding taxes paid on net exercise of stock options Withholding taxes paid on net exercise of stock options Withholding taxes paid on net exercise of stock options Follow On Offering [Member] Follow-on offering. Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items] Related Party Transaction [Line Items] Underwriters. Underwriters [Member] Accounts, Notes, Loans and Financing Receivable [Line Items] Business Combination [Table] Entity Registrant Name Debt Disclosure [Text Block] Debt Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table] 2027 Finite-Lived Intangible Asset, Expected Amortization, Year Two Other Nonoperating Income (Expense), Total Other income, net Other Nonoperating Income (Expense) Other (expense) income, net Additional Paid in Capital, Total Additional Paid in Capital Additional paid-in capital Subsequent Events [Abstract] Consolidated Entities [Domain] Finite-Lived Intangible Asset, Expected Amortization, Year Three 2028 Measurement Frequency [Axis] Proceeds from Issuance of Common Stock Proceeds from follow-on public offerings, net of issuance costs Net aggregate proceeds Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] Issuance of redeemable convertible preferred stock. Issuance Of Redeemable Convertible Preferred Stock Issuance of Series F redeemable convertible preferred stock (inclusive of deemed dividend of $410 to accrete to redemption value), value Entity Common Stock, Shares Outstanding Liability Class [Axis] Consolidation Items [Axis] Purchases of property and equipment Payments to Acquire Property, Plant, and Equipment, Total Payments to Acquire Property, Plant, and Equipment Purchase of property and equipment Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period Number of shares, Granted Assets Total assets Property, Plant and Equipment [Table] Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term Weighted Average Remaining Contractual Term (Years), Exercisable Income Statement [Abstract] Finite Lived Intangible Assets Amortization Expense After Year Four Finite lived intangible assets amortization expense after year four. Thereafter License and collaboration agreements. License and Collaboration Agreements [Line Items] Sale of stock Sale of Stock, Number of Shares Issued in Transaction Stock Issued During Period, Shares, New Issues Common shares offering Issuance of common stock, net of issuance costs, shares Temporary Equity, Shares Authorized Redeemable convertible preferred stock, shares authorized Authorized Shares Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period Number of shares, Vested Business Combination [Abstract] Open Market Sale Agreement [Member] Open Market Sale Agreement. Collaboration agreement transaction price Collaboration agreement transaction price. Collaboration Agreement Transaction Price Earnings Per Share, Diluted, Total Earnings Per Share, Diluted Net loss per share , diluted Net loss per share attributable to common stockholders, diluted Schedule of Selected Financial Information with Respect to Single Operating Segment Schedule of Segment Reporting Information, by Segment [Table Text Block] Operating Segments [Member] Significant accounting policy. Significant Accounting Policy [Line Items] City Area Code Series b redeemable convertible preferred stock. Series B Redeemable Convertible Preferred Stock [Member] Series B Redeemable Convertible Preferred Stock Debt Instrument, Face Amount Original principal amount Principal amount of convertible promissory note including accrued interest External research and development expenses. External Research and Development Expenses [Member] External Research and Development Expenses Business Combination [Line Items] Series e redeemable convertible preferred stock. Series E Redeemable Convertible Preferred Stock [Member] Series E Redeemable Convertible Preferred Stock Counterparty Name [Domain] Deferred offering costs accounts payable Deferred Offering Costs Accounts Payable Deferred offering costs accounts payable. Stock Issued During Period, Value, Employee Stock Purchase Plan Stock-based compensation expense under ESPP SafeGuard Healthcare, LLC [Member] SafeGuard Healthcare, LLC. SafeGuard Healthcare, LLC Operating Lease, Weighted Average Remaining Lease Term Weighted-average remaining lease term (years) Segment Reporting Information [Line Items] Reverse stock split conversion ratio Stockholders' Equity Note, Stock Split, Conversion Ratio Lease, Cost Total lease cost Total lease cost Property, Plant and Equipment, Net Property and equipment, net Property and equipment, net Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Exercisable, Number Number of Outstanding Options, Exercisable Loss from operations Operating Income (Loss) Loss from operations Retained Earnings [Member] Accumulated Deficit Royalties. Royalties Royalties Share-Based Payment Arrangement, Noncash Expense, Total Share-Based Payment Arrangement, Noncash Expense Stock-based compensation expense Stock issuance costs Payments of Stock Issuance Costs Stock issuance costs Operating Lease, Weighted Average Discount Rate, Percent Weighted-average discount rate Operating Lease, Liability, Noncurrent Operating lease liabilities, net of current portion Fair Value, Inputs, Level 1 [Member] Level 1 Class of Stock [Line Items] Cash Provided by (Used in) Financing Activity, Including Discontinued Operation Net cash provided by financing activities Lease, Cost [Table Text Block] Components of Lease Expense Extinguishment of Debt, Type [Domain] Schedule of Conversions of Stock [Table Text Block] Summary of Redeemable Convertible Preferred Stock Nonoperating Income (Expense) [Abstract] Other income (expense), net: Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block] Schedule of Antidilutive Securities Excluded from Computation of Diluted Net Loss Per Share Attributable to Common Stockholders Lepu Biotech Co., Ltd. Lepu Biotech Co., Ltd. [Member] Lepu Biotech Co., Ltd. Entity Interactive Data Current Statement of Income Location, Balance [Domain] Cash Provided by (Used in) Operating Activity, Including Discontinued Operation [Abstract] Operating Activities Increase (Decrease) in Other Noncurrent Liabilities Other liabilities Series c redeemable convertible preferred stock. Series C Redeemable Convertible Preferred Stock [Member] Series C Redeemable Convertible Preferred Stock Entity Tax Identification Number Revenues [Abstract] Revenues Long-Term Debt, Type [Axis] Danforth Advisors, LLC. Danforth Advisors, LLC [Member] Danforth Advisors, LLC Rule 10b5-1 Arr Modified Flag Rule 10b5-1 Arr Modified Flag. Rule 10b5-1 Arrangement Modified Local Phone Number Number of shares, Expected to vest Share Based Compensation Arrangement by Share Based Payment Award, Equity Instruments Other than Options, Expected to Vest Share-based compensation arrangement by share-based payment award, equity instruments other than options, expected to vest. Two thousand twenty four plan. Two Thousand Twenty Four Plan [Member] 2024 Plan Accounting Policies [Abstract] Commercial And Development Revenue [Member] Commercial and development revenue. Commercial and Development Revenue Lessee, Operating Lease, Liability, to be Paid, Year Four 2030 Cash and Cash Equivalents [Member] Cash Equivalents Class of Stock [Domain] Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant Common stock available for future issuance Unrecognized stock-based compensation expense expected to be recognized over weighted-average period Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition ANI agreement ANI Agreement [Member] ANI Agreement. Stock, Class of Stock [Table] Entity Emerging Growth Company Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term Weighted Average Remaining Contractual Term (Years), Vested and expected to vest Business Combination, Recognized Asset Acquired to Liability Assumed, Excess (Less), and Goodwill Total fair value of consideration paid